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In 1872, the Shadowhunters signed the first of the Accords, becoming the first step in the peace negotiations with the Downworld populace.
In 1878, the Shadowhunters of the London Institute faced the Magister and his clockwork army, whose intent was to create a formidable new race of half-Nephilim, half-demon beings, with the first of their kind, Tessa Gray, capable of several unknowable abilities—one of which was the power to Change when the demon parent is an Eidolon.
They advocated and upheld their belief that they must increase their numbers by turning more mundanes with the Mortal Cup, and that they must once again be united and up in arms primarily against Downworlders.
Despite their ancestry, Shadowhunters are mortal and therefore vulnerable to old age and death; however, their angelic blood endows them with special abilities that allow them to achieve feats beyond what's humanly possible through the application of angelic runes.
In the Bible, the Nephilim were the offspring of humans and angels, although it is unknown if they really existed or not.
In the Shadowhunter's Codex, the Angel Raziel is said to have named Jonathan and his new breed after the Nephilim of the Bible, even making references as such, though this too is unknown as no official records exists of what exactly happened that day.
For some reason, undisclosed at this point, 1234 is a significant date among Shadowhunters: along with the Nephilim motto, the date is inscribed on the base of the statue by the entrance to the Silent City in New York.
The 11th and 13th centuries are also cited by the Shadowhunter's Codex as the beginning and peak, respectively, of the promotion of the race of the Nephilim, when new members were being sought for and recruited after the death of the first Shadowhunters, and the two points in time pointed out as when the first edition of the Codex was written, the first being the time given in the presumption that the Codex was written by Jonathan Shadowhunter, and the second estimated based on modern research and dating techniques.